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Levsin (Hyoscyamine [hi OS ah meen]) Frequently Asked Questions
Part 2: Side effects, pregnancy, and antibiotic-associated diarrhea.
 More of this Feature
• Part 1: Prescribing and Dosing Information
 Related Resources
• Anticholinergics
• Constipation
• Fighting Dehydration
 Elsewhere on the Web
• Intestinal Antispasmodics

Generic name: Hyoscyamine
Other brand name: Anaspaz

What are the side effects?
     The most serious side effects from Levsin are confusion, blurred vision, and difficulty in urination, and decreased sweating. If you experience these symptoms call your doctor immediately. Take care to stay hydrated, particularly in hot weather.

     Other common side effects include headache, nausea, constipation, rash, and vomiting. See the Levsin Side Effects page for a complete list.

What medications can Levsin interact with?
     Levsin can interact with several drugs. Tell the prescribing physician about all drugs and nutritional supplements you are taking, especially those from the following list which may interact with Levsin.

  • Antacids
  • Anticoagulants
  • Antidepressants
  • Antihistamines
  • Amantadine
  • Cardiac rhythm regulators
  • Cimetidine
  • Digoxin
  • Metoclopramide
  • Monoamine oxidase (MAO) inhibitors
  • Potassium chloride
  • Prednisone
  • Sedatives
  • Thiazide diuretics

Are there any food interactions?
     Consuming alcohol while taking Levsin could have a sedative effect and cause tiredness or sleepiness. Take care to avoid alcohol from unexpected sources, such as over the counter cough suppressants or cold products (Nyquil, for example).

     Levsin may also cause constipation. A high fiber diet and plenty of water should help to negate this effect.

Is Levsin safe during pregnancy?
     The FDA has classified Levsin as a type C drug. The belladonna portion of Levsin has not been shown to cause any problems for pregnant women. However, the barbiturate portion does increase the risk of birth defects and bleeding in newborns. Levsin does pass into breast milk.

     Levsin should only be used during pregnancy if clearly needed. Notify the prescribing doctor if you become pregnant while taking Levsin. The potential for serious side effects in an infant should be weighed against the usefulness of the medication to the mother.

Can Levsin cause any sexual side effects?
     Levsin can cause impotence in men, and supression of breast milk in nursing mothers.

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