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Ulcer

By , About.com Guide

Updated November 27, 2011

About.com Health's Disease and Condition content is reviewed by the Medical Review Board

Definition: An ulcer is a lesion where there is an area of damaged or absent surface tissue, and exposed deeper tissue below. When most people think of "ulcer," they think of stomach ulcers (or peptic ulcers), which are most often caused by a bacteria. However, ulcers can form in many different places on the body and they can occur for a variety of reasons.

In inflammatory bowel disease (IBD), ulcers form on the insides of the intestine. In ulcerative colitis, the ulcers are found in the inner mucus lining of the intestine. In Crohn's disease, the inflammation goes deeper, and ulcers can permeate into all the layers of the bowel wall.

People with IBD also sometimes develop shallow ulcers in the mouth, known as canker sores, or medically as (aphthous stomatitis), which is an extra-intestinal condition. Canker sores are annoying, but not usually serious. They're common among the general population, too.

Pronunciation: UL-sur

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