Methotrexate:
Methotrexate is a very effective, and usually safe, drug with a long list of dose-dependent side effects. Patients with IBD and Crohn's do not get high doses, so, although all of these side effects are possible, IBD and Crohn's patients are less likely to get them. Methotrexate is to be taken only in close consultation and with close followup from a doctor, and any and all side effects should be discussed with your physician.
Temporary Side Effects:
Check with your doctor if any of the following side effects continue or are bothersome:
- Acne
- Boils
- Lack of appetite
- Nausea or vomiting
- Pale skin
- Sensitivity to sunlight
- Itching or rash
- Temporary hair loss
Notify Your Doctor if you Experience::
- Back pain
- Dark urine
- Dizziness
- Drowsiness
- Headache
- Unusual weakness or fatigue
- Yellow eyes or skin (jaundice)
Notify Your Doctor Immediately if you Experience::
- Diarrhea
- Reddening of skin
- Sores on mouth and lips
- Stomach pain
- Allergic reaction
- Blurred vision
- Chest pains
- Confusion
- Dead or loose skin layers
- Fever or chills
- Pinpoint red spots on skin
- Painful peeling of skin patches
- Painful or difficult urination
- Red blisters or ulcers on the lip, mouth, eye, nasal passages, and genital area
- Reddening of the skin with or without hair loss
- Seizures (convulsions)
- Shortness of breath, cough, hoarseness or wheezing
- Side or lower back pain
- Sloughing of skin , muscle and bone
- Unusual bleeding or bruising
Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor. This information is meant only as a guideline -- always consult a physician or pharmacist for complete information about prescription medications.
