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Prednisone Frequently Asked Questions

Prednisone Has Many Troubling Side Effects, But Is Cheap And Effective


Updated June 16, 2014

Adrenal Glands

Prednisone, and other steroids, are similar to a compound produced in the adrenal glands. If it's not used carefully, steroids can cause the adrenal glands to slow down or shut down their natural production of cortisol.

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How much do you know about prednisone? Take the quiz and find out!

What Is Prednisone?

Prednisone is a type of drug known as a corticosteroid. It closely resembles a substance made by the human adrenal glands. Steroids that are made by the human body work to reduce inflammation and to regulate the intake of salt. The body produces more steroids when it is stress, such as during an illness. This is why they are sometimes referred to as "stress hormones."

What Are The Side Effects Of Prednisone?

Side effects of prednisone that can prove troublesome include increased appetite, weight gain, hair growth, acne, mood changes and difficulty sleeping. See the prednisone side effects page for a more complete list.

The more serious side effects of prednisone include cataracts, glaucoma, osteoporosis, and bone damage in hips. These side effects are permanent and occur only after long-term use. If you have concerns about these side effects, you should speak to your physician regarding these risks.

How Is Prednisone Taken?

Prednisone should be taken exactly as prescribed by the doctor. A physician will tailor the dosage to the needs of each individual patient. In order for prednisone to have the desired effect on the body, it must be taken at certain regular intervals. DO NOT stop taking prednisone suddenly without consulting your physician. Prednisone is a drug that must be tapered down slowly over a number of days -- and in some cases, even over weeks or months.

In order to prevent the stomach upset that sometimes occurs with prednisone, it can be taken with a meal or a snack.

Why Is Prednisone Prescribed?

Prednisone may be prescribed for many conditions including inflammatory bowel disease (IBD), allergic rhinitis (hay fever), rheumatoid arthritis, and ankylosing spondylitis.

What Do I Do If I Miss A Dose?

If you miss a dose, take it as soon as you remember. If your next dose of prednisone should be taken soon, just take that dose. Don't double up, or take more than one dose at a time.

Who Should Not Take Prednisone?

Tell your doctor if you have ever had any of the following conditions:

What Medications Can Prednisone Interact With?

Prednisone may interact with the following medications:

  • Anticoagulants
  • Barbiturates
  • Cholestyramine (Questran)
  • Chronic high dose aspirin
  • Ephedrine (found in cold medications)
  • Ketoconazole
  • Phenobarbital
  • Phenytoin
  • Rifampin
  • Troleandomycin

Is Prednisone Safe During Pregnancy?

The FDA has classified prednisone as a type C drug. This means that it is not known what effect pregnancy will have on an unborn baby. Notify the prescribing doctor if you become pregnant while taking prednisone. Prednisone does pass into breast milk, and could affect a nursing infant.

How Long Can Prednisone Be Taken Safely?

In most cases, it is advisable to taper off prednisone as soon as symptoms subside.

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