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What You Need To Know About Entocort EC (Budesonide)

Dosage, Side Effects, And Use During Pregnancy For This Corticosteroid Drug


Updated May 31, 2014

What is Entocort EC?

Entocort EC is used to treat mild to moderate Crohn's disease involving the ileum and/or the ascending colon. Entocort EC is a nonsystemic corticosteroid that is released into the intestine and works to reduce inflammation. Because 90% of the drug is released in the intestine and not into the bloodstream, it causes fewer side effects than other corticosteroids (i.e., prednisone).

How is Entocort EC taken?

Entocort EC is normally taken in capsule form in the morning with or without food. Entocort EC should be swallowed whole and should never be crushed, chewed or broken in half.

Why is Entocort EC prescribed?

Even though Entocort EC belongs to the class of drugs known as corticosteroids, it may be more effective and have fewer side effects than other medications in this category.

What do I do if I miss a dose?

If you miss a dose, take it as soon as you remember. If your next dose should be taken soon, just take that dose. Don't double up, or take more than one dose at a time.

Who should not take Entocort EC?

Tell your doctor if you have ever had any of the following conditions:

  • Any condition that suppresses the immune system
  • Cataracts
  • Diabetes (or a family history)
  • Glaucoma (or a family history)
  • High blood pressure
  • Liver disease
  • Osteoporosis
  • Tuberculosis
  • Ulcers


What are the side effects?

Common side effects of Entocort EC include headache, respiratory infection, and nausea.

Are there any sexual side effects?

Entocort EC is not known to cause any sexual side effects in either men or women.

What medications can Entocort EC interact with?

Ketoconazole can intefere with the way the liver processes Entocort EC.

Are there any food interactions?

Grapefruit or grapefruit juice can interact with Entocort EC and cause more of it to be released into the bloodstream.

Is Entocort EC safe during pregnancy?

The FDA has classified Entocort EC as a type C drug. The effect that Entocort EC has on an unborn child has not been studied extensively. Entocort EC should only be used during pregnancy if clearly needed. Notify the prescribing doctor if you become pregnant while taking Entocort EC. Entocort EC does pass into breast milk and can affect a nursing infant.

How long is it safe to use Entocort EC?

Entocort EC has been approved for use for up to 8 weeks.

Is there anything else I should know about Entocort EC?

People taking Entocort EC should avoid exposure to anyone who has chickenpox or the measles or who has been vaccinated with a live virus. Entocort may also suppress the response of the hypothalamus-pituitary-adrenal (HPA), and therapy may be necessary before surgery (including dental surgery) or other stressful events.

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  6. What You Need To Know About Entocort EC (Budesonide)

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